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Good factory supply good p-Bromophenoxyacetic acid 1878-91-7
- Molecular Formula: C8H7BrO3
- Molecular Weight: 231.046
- Appearance/Colour: White or cream crystalline powder
- Vapor Pressure: 3.96E-05mmHg at 25°C
- Melting Point: 149-153 °C(lit.)
- Refractive Index: 1.579
- Boiling Point: 337.9 °C at 760 mmHg
- PKA: 3.09±0.10(Predicted)
- Flash Point: 158.2 °C
- PSA： 46.53000
- Density: 1.641 g/cm3
- LogP: 1.91250
p-Bromophenoxyacetic acid(Cas 1878-91-7) Usage
|
Purification Methods |
Crystallise the acid from EtOH or H2O (m 161.4-161.8o). [Hayes & Branch J Am Chem Soc 65 1555 1943, Beilstein 6 III 747, 6 IV 1052.] |
|
General Description |
4-Bromophenoxyacetic acid, also known as p-bromophenoxyacetate, is a phenoxyalkanoic acid derivative. It is a chemical elicitor that can induce β-glucuronidase (GUS) activity in rice. |
InChI:InChI=1/C8H7BrO3/c9-6-1-3-7(4-2-6)12-5-8(10)11/h1-4H,5H2,(H,10,11)
1878-91-7 Relevant articles
Design, docking, synthesis, and characterization of novel N'(2-phenoxyacetyl) nicotinohydrazide and N'(2-phenoxyacetyl)isonicotinohydrazide derivatives as anti-inflammatory and analgesic agents
Al-Ostoot, Fares Hezam,Khanum, Shaukath Ara,M, Pallavi H,Vivek, Hamse Kameshwar
, (2021/09/14)
Inflammation is the complex biological r...
Design, synthesis and biological evaluation of oxime lacking Psammaplin inspired chemical libraries as anti-cancer agents
Ali, Kasim,Chaturvedi, Priyank,Datta, Dipak,Kumar M, Srinivas Lavanya,Meena, Sanjeev,Panda, Gautam
, (2020/10/02)
In this study, we attempted the chemical...
Modulation of DNA damage response by targeting ATM kinase using newly synthesized di-phenoxy acetamide (DPA) analogs to induce anti-neoplasia
Al-Ostoot, Fares Hezam,Sherapura, Ankith,Malojirao, Vikas H.,Thirusangu, Prabhu,Al-Muhimeed, Tahani I.,Khanum, Shaukath Ara,Prabhakar
, p. 1344 - 1360 (2021/06/14)
Background: Imbalance and instability in...
Targeting HIF-1α by newly synthesized Indolephenoxyacetamide (IPA) analogs to induce anti-angiogenesis-mediated solid tumor suppression
Al-Ostoot, Fares Hezam,Sherapura, Ankith,V, Vigneshwaran,Basappa, Giridhara,H.K, Vivek,B.T, Prabhakar,Khanum, Shaukath Ara
, p. 1328 - 1343 (2021/05/03)
Background: Hypoxic microenvironment is ...
1878-91-7 Process route
-
-
6964-29-0
ethyl 2-(4-bromophenoxy)acetate
-
-
1878-91-7
(4-bromophenoxy)acetic acid
| Conditions | Yield |
|---|---|
|
With
sodium hydroxide;
In
ethanol; water;
for 8h;
Reflux;
|
86%
|
|
With
lithium hydroxide monohydrate; water;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 4h;
|
73%
|
|
With
potassium hydroxide;
|
|
|
With
lithium hydroxide;
In
tetrahydrofuran; water;
at 20 ℃;
|
|
|
ethyl 2-(4-bromophenoxy)acetate;
With
lithium hydroxide monohydrate;
In
tetrahydrofuran; water;
at 20 ℃;
Inert atmosphere;
With
hydrogenchloride;
In
tetrahydrofuran; water;
at 20 ℃;
Inert atmosphere;
|
|
|
With
water; lithium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
for 3h;
|
|
|
ethyl 2-(4-bromophenoxy)acetate;
With
sodium hydroxide;
In
methanol; water;
for 1h;
With
hydrogenchloride;
In
water;
|
|
|
With
water; sodium hydroxide;
In
ethanol;
at 20 ℃;
for 4h;
|
|
|
With
water; lithium hydroxide;
In
tetrahydrofuran;
|
|
|
With
sodium hydroxide;
In
ethanol; water;
Reflux;
|
|
|
With
ethanol; sodium hydroxide;
Reflux;
|
|
|
With
lithium hydroxide;
In
tetrahydrofuran; methanol; water;
at 20 ℃;
|
-
-
282116-88-5
4-bromophenoxy acetic acid t-butyl ester
-
-
1878-91-7
(4-bromophenoxy)acetic acid
| Conditions | Yield |
|---|---|
|
With
trifluoroacetic acid;
In
dichloromethane; water;
at 20 ℃;
for 66h;
|
91%
|
|
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 3h;
|
1878-91-7 Upstream products
-
2555-49-9
phenoxyacetic acid ethyl ester
-
106-41-2
4-bromo-phenol
-
79-11-8
chloroacetic acid
-
122-59-8
2-phenoxyacetic acid
1878-91-7 Downstream products
-
4841-23-0
(4-bromophenoxy)acetic acid methyl ester
-
16737-86-3
4-Brom-phenoxyessigsaeure- <2-dimethylamino-aethylester>
-
65569-44-0
4-[2-(4-Bromo-phenoxy)-acetylamino]-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide
-
71475-48-4
<4-brom-phenoxy> -essigsaeure- <3-diaethylamino-propylamid>
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