Danazol

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1.What is the Danazol ?

White Solid

Danazol, also known as 17α-pregn-2,4-dien-20-yno-[2,3-d]isoxazol-17-ol, is a synthetic steroid with diverse biological effects. It is a weak androgen and an anabolic steroid derivative of ethisterone, with mild androgenic side effects. Danazol has little estrogenic or progestogenic activity, despite the presence of the 17α-ethinyl group. It binds to sex hormone-binding globulin (SHBG), decreasing the hepatic synthesis of this estradiol and testosterone carrier, which results in an increase in free testosterone. Danazol inhibits the production of FSH and LH by the hypothalamus and pituitary, and it also binds to PRs, GRs, ARs, and ERs. Although its exact mechanism of action is unclear, it is known to alter endometrial tissue, making it inactive and atrophic, which contributes to its effectiveness in treating endometriosis. Danazol is also used to treat hereditary angioedema and fibrocystic breast disease. It is a white solid and is commercially available under the brand name Dancocrine by Sanofi Aventis.

2.What is the CAS number for Danazol ?

The CAS number of Danazol is 17230-88-5.

3.What are another words for Danazol ?

Synonyms?for?Danazol 17230-88-5:17a-Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol(8CI);1H-Cyclopenta[7,8]phenanthro[3,2-d]isoxazol-1-ol, 1-ethynyl-2,3,3a,3b,4,5,10,10a,10b,11,12,12a-dodecahydro-10a,12a-dimethyl-(7CI);Bonzol;Cyclomen;Danalem;Danazolum;Danocrine;Danol;Ladogal;NSC 270916;Win 17757;Winobanin;

4.What is Danazol (17230-88-5) used for?

Anterior pituitary supressant. Anabolic steroid derivative of ethisterone, with mild androgenic side effects (an impeded androgen). Antigonadotropin

Danazol, a synthetic androgen, has been used to treat the pruritus of primary biliary cirrhosis, urticaria, and also idiopathic pruritus. It has been used for treatment of pruritus associated with polycythemia vera and systemic lupus erythematosus.

InChI:InChI=1/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16-,17+,18+,20?,21?,22+/m1/s1

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5.Buy Danazol with the best price .

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