MonoMethyl auristatin E

Factory Sells Best Quality MonoMethyl auristatin E 474645-27-7 with ISO standards We supply high quality MonoMethyl auristatin E (CAS 474645-27-7), in stock, factory directly supply to clients, lower prices, more competitiveness.

What is the MonoMethyl auristatin E ?

MonoMethyl auristatin E is , while it's Molecular Formula is C39H67N5O7. Dolastatin 10 is a natural antimitotic and antineoplastic agent that binds to tubulin and inhibits tubulin polymerization. Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. MMAE is typically coupled to the antibody via a protease-cleavable linker, allowing separation of the drug from the antibody following intracellular localization.[Cayman Chemical]

What is the CAS number for MonoMethyl auristatin E ?

The CAS number of MonoMethyl auristatin E is 474645-27-7.

More information of MonoMethyl auristatin E 474645-27-7 are:

What is MonoMethyl auristatin E (474645-27-7) used for?

MMAE is a synthetic antineoplastic agent. Because of its toxicity, it cannot be used as a drug itself; instead, it is linked to a monoclonal antibody (MAB) which directs it to the cancer cells. Monomethyl auristatin E or MMAE is 100-1000 times more potent than doxorubicin. It is a very potent antimitotic agent that inhibits cell division by blocking the polymerization of tubulin.

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How to get the best price on MonoMethyl auristatin E?

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